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A new class of cardiotonic agents: structure-activity correlations for natural and synthetic analogues of the alkaloid pumiliotoxin B (8-hydroxy-8-methyl-6-alkylidene-1-azabicyclo[4.3.0]nonanes)DALY, J. W; MCNEAL, E. T; OVERMAN, L. E et al.Journal of medicinal chemistry (Print). 1985, Vol 28, Num 4, pp 482-486, issn 0022-2623Article

INHIBITION OF CALCIUM-DEPENDENT ATPASE FROM SARCOPLASMIC RETICULUM BY A NEW CLASS OF INDOLIZIDINE ALKALOIDS, PUMILIOTOXINS A, B, AND 251 DTAMBURINI R; ALBUQUERQUE EX; DALY JW et al.1981; J. NEUROCHEM.; ISSN 0022-3042; GBR; DA. 1981; VOL. 37; NO 3; PP. 775-780; BIBL. 23 REF.Article

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Enantioselective total syntheses of pumiliotoxin B and pumiliotoxin 251D. A general entry to the pumiliotoxin A alkaloids via stereospecific iminium ion-vinylsilane cyclizationsOVERMAN, L. E; BELL, K. L; ITO, F et al.Journal of the American Chemical Society. 1984, Vol 106, Num 15, pp 4192-4201, issn 0002-7863Article

Pumiliotoxin B-like alkaloid in extracts of the skin of the Australian myobatrachid from Pseudophryne coriacea: effects on the systemic blood pressure of experimental animals and the rat heartFALCONIERI ERSPAMER, G; SEVERINI, C; ERSPAMER, V et al.Neuropharmacology. 1989, Vol 28, Num 4, pp 319-328, issn 0028-3908Article

The effect of pumiliotoxin-B on the excitability of bullfrog sympathetic neuronsSCHOFIELD, G. G; WEIGHT, F. F; IKEDA, S. R et al.European journal of pharmacology. 1988, Vol 147, Num 1, pp 39-48, issn 0014-2999Article

Pumiliotoxin B binds to a site on the voltage-dependent sodium channel that is allosterically coupled to other binding sitesGUSOVSKY, F; ROSSIGNOL, D. P; MCNEAL, E. T et al.Proceedings of the National Academy of Sciences of the United States of America. 1988, Vol 85, Num 4, pp 1272-1276, issn 0027-8424Article

Pharmacology of the alkaloid pumiliotoxin-B. II Possible involvement of calcium and sodium-dependent processes in nerve and skeletal muscleRAO, K. S; WARNICK, J. E; DALY, J. W et al.The Journal of pharmacology and experimental therapeutics. 1987, Vol 243, Num 2, pp 775-783, issn 0022-3565Article

HIGHLY STEREOCONTROLLED REDUCTION OF ALPHA '-ALKOXYENONES TO GIVE EITHER THE THREO OR ERYTHRO ALLYLIC 1,2-DIOL. ASSIGNMENT OF THE THREO CONFIRGURATION TO THE C-15, C-16 DIOL OF PUMILIOTOXIN BOVERMAN LE; MCCREADY RJ.1982; TETRAHEDRON LETT.; ISSN 0040-4039; GBR; DA. 1982; VOL. 23; NO 23; PP. 2355-2358; BIBL. 18 REF.Article

A NEW CLASS OF INDOLIZIDINE ALKALOIDS FROM THE POISON FROG, DENDROBATES TRICOLOR. X-RAY ANALYSIS OF 8-HYDROXY-8-METHYL-6-(2'-METHYLHEXYLIDENE)-1-AZABICYCLO (4.3.0) NONANEDALY JW; TOKUYAMA T; FUJIWARA T et al.1980; J. AMER. CHEM. SOC.; USA; DA. 1980; VOL. 102; NO 2; PP. 830-836; BIBL. 18 REF.Article

Pumiliotoxin alkaloids: relationship of cardiotonic activity to sodium channel activity and phosphatidylinositol turnoverDALY, J. W; MCNEAL, E; GUSOVSKY, F et al.Journal of medicinal chemistry (Print). 1988, Vol 31, Num 2, pp 477-480, issn 0022-2623Article

Pumiliotoxin B-like alkaloid in extracts of the skin of the Australian myobatrachid frog Pseudophryne coriacea : effects on blood pressure and heart of the rabbitSEVERINI, C; TITA, B; BOLLE, P et al.Archives internationales de pharmacodynamie et de thérapie. 1992, Vol 317, pp 56-66, issn 0003-9780Conference Paper

The effects of pumiliotoxin-B on sodium currents in guinea pig hippocampal neuronsSHERIDAN, R. E; DESHPANDE, S. S; LEBEDA, F. J et al.Brain research. 1991, Vol 556, Num 1, pp 53-60, issn 0006-8993Article

Cardiotonic activities of pumiliotoxin B, pyrethroids and a phorbol ester and their relationships with phosphatidylinositol turnoverDALY, J. W; MCNEAL, E. T; GUSOVSKY, F et al.Biochimica et biophysica acta. 1987, Vol 930, Num 3, pp 470-474, issn 0006-3002Article

Stimulation of phosphoinositide breakdown in brain synaptoneurosomes by agents that activate sodium influx: antagonism by tetrodotoxin, saxitoxin, and cadmiumGUSOVSKY, F; MCNEAL, E. T; DALY, J. W et al.Molecular pharmacology. 1987, Vol 32, Num 4, pp 479-487, issn 0026-895XArticle

Convergent approach to pumiliotoxin alkaloids. Asymmetric total synthesis of (+)-pumiliotoxins A, B, and 225FAOYAGI, Sakae; HIRASHIMA, Shintaro; SAITO, Kosuke et al.Journal of organic chemistry. 2002, Vol 67, Num 16, pp 5517-5526, issn 0022-3263, 10 p.Article